GeneProof OmniPlex QF PCR Kit
The QF PCR kits are designed for quick diagnostics of chromosome 13, 18, 21 aneuploidy and sex chromosome aneuploidy.
These aneuploidies represent over 80 % of all significant chromosomal aberrations related to serious genetic disorders such as Down syndrome, Edwards syndrome, Patau syndrome, Turner syndrome, Klinefelter syndrome, etc.
The multiplex QF-PCR (Quantitative-fluorescent Polymerase Chain Reaction) method is based on the amplification of a large number of fluorophore labelled DNA fragments (STR markers) at chromosomes during a single reaction.
Besides the basic version of the GeneProof OmniPlex QF PCR Kit we offer alternative kit versions to be used in case of insufficiently informative results from an examination performed using the GeneProof OmniPlex QF-PCR Kit or for pathology detection verification. You can use the alternative versions independently as well; selection of a suitable diagnostic kit version depends on the individual customer's requirements
|Target Sequence||25 STR loci DNA sequences at the 13, 18, 21, X and Y chromosomes|
|Qualitative detection||mutation present × not present|
Homozygote – alleles with the same length feature just one peak
|Specimen||whole blood, amniotic fluid, tissue|
|Kit Storage||-85 °C to -10 °C|
QIAamp DNA Mini Mit (Qiagen)
QIAamp DNA Blood Mini Kit (Qiagen)
|Supported Devices **||
Applied Biosystems 310 Genetic Analyzer
quality management system is certified in compliance with the requirements of the standard ISO 13485
|External Quality Assessment||
regularly tested by External Quality Assessment panels - results at www.geneproof.com
** GeneProof OmniPlex QF PCR Kit has been designed for use with Applied Biosystems genetic analyzers supporting 5-Dye Data Collection.
|GeneProof OmniPlex QF PCR Kit||OMNISET/025||quantitative fluorescent PCR||25 reactions|
|GeneProof OmniPlex QF PCR Kit||OMNISET/050||quantitative fluorescent PCR||50 reactions|