GeneProof PAI-1 Genotyping PCR Kit

The PCR kit is designed to detect polymorphism in promoter of the PAI-1 gene by the real-time Polymerase Chain Reaction (PCR) method.

The method consists in amplification and detection of the target sequence using allele specific fluorophore labelled probes. The target sequence is insertion-deletion polymorphism of guanosine 4G/5G in site 675. Presence of wild-type allele (5G/5G) is detected in the FAM fluorescent channel and mutant allele (4G/4G) in the HEX fluorescent channel. In case of heterozygous genotype (4G/5G) a signal is detected in both channels. Detection kit contains Ready-to-Use Master Mix and takes advantage of the "hot start" technology, minimizing non-specific reactions and assuring maximum sensitivity. Kit is designed for in vitro diagnostic.

PRODUCT ADVANTAGES

SINGLE TUBE READY-TO-USE MASTER MIX

• Contains all components for PCR amplification
• Reduces the need of qualified laboratory staff
• Enables quick and reliable results

UNIVERSAL PCR PROFILE

• Uniform reaction format
• All PCR Kits from the group Thrombotic Mutations are easily combinable with each othe
• Simplifies laboratory workflow

COMPATIBLE WITH A WIDE RANGE OF REAL-TIME PCR DEVICES

CE IVD CERTIFIED DIAGNOSTIC TEST