GeneProof MTHFR A1298C PCR Kit

The PCR kit is designed to detect A1298C polymorpism in the gene for methylenetetrahydrofolate reductase (MTHFR) by the real-time Polymerase Chain Reaction (PCR).

The method consists in amplification and detection of the target sequence using allele specific fluorophore labelled probes. The target sequence is the single nucleotide adenine/cytosine polymorphism in site 1298 (A1298C). Presence of wild-type allele (A1298A) is detected in the FAM fluorescent channel and mutant allele (C1298C) in the HEX fluorescent channel. In case of heterozygous genotype (A1298C) a signal is detected in both channels. Detection kit contains Ready-to-Use Master Mix and takes advantage of the "hot start" technology, minimizing non-specific reactions and assuring maximum sensitivity. Kit is designed for in vitro diagnostics.

PRODUCT ADVANTAGES

SINGLE TUBE READY-TO-USE MASTER MIX

• Contains all components for PCR amplification
• Reduces the need of qualified laboratory staff
• Enables quick and reliable results

UNIVERSAL PCR PROFILE

• Uniform reaction format
• All PCR Kits from the group Thrombotic Mutations are easily combinable with each other
• Simplifies laboratory workflow

COMPATIBLE WITH A WIDE RANGE OF REAL-TIME PCR DEVICES

CE IVD CERTIFIED DIAGNOSTIC TEST